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Neurotoxin Studies

Clinical studies involving neurotoxins you can study to further expand your knowledge.

  1.  Karimi N, Kashkouli MB, Sianati H, Khademi B.  Techniques of Eyebrow Lifting: A Narrative Review.  J Ophthalmic Vis Res. 2020 Apr-Jun;15(2):218-235. doi: 10.18502jovr.v15i2.6740. eCollection 2020 Apr-Jun. Review. PubMedPMID: 32308957; PubMed Central PMCID: PMC7151508.
  2. Karapantzou C, Jakob M, Canis M.  Neurotoxin injection in benign submandibular gland hypertrophy: A first choice treatment.   Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):217-220. doi: 10.1002/lio2.363. eCollection 2020 Apr. PubMed PMID: 32337352; PubMed Central PMCID: PMC7178459.
  3. Bertucci V, Solish N, Kaufman-Janette J, Yoelin S, Shamban A, Schlessinger J, Snyder D, Gallagher C, Liu Y, Shears G, Rubio RG. DaxibotulinumtoxinA for Injection has a prolonged duration of response in the treatment of glabellar lines: Pooled data from two multicenter, randomized, double-blind, placebo-controlled, phase 3 studies (SAKURA 1 and SAKURA 2).  J Am Acad Dermatol. 2020 Apr;82(4):838-845. doi: 10.1016/j.jaad.2019.06.1313. Epub 2019 Nov 29. PubMed PMID: 31791824.
  4. Park JY, Sunga O, Wanitphakdeedecha R, Frevert J.  Neurotoxin Impurities: A Review of Threats to Efficacy.  Plast Reconstr Surg Glob Open. 2020 Jan;8(1):e2627. doi: 10.1097/GOX.0000000000002627. eCollection 2020 Jan. PubMed PMID: 32095419; PubMed Central PMCID: PMC7015620.
  5. Carruthers JD, Fagien S, Joseph JH, Humphrey SD, Biesman BS, Gallagher CJ, Liu Y, Rubio RG, Cohen JL, Ho S, Cox SE, Soderberg J, Swift A, Borsuk D, Papanastasiou V, Shamban A, Simzar S, Bertucci V, Waller B, Boyd C, Katz M, Churchill L, Smith S, Burgess C, Dhir K, Draelos Z, Draelos M, Rosen N, Muhn C, Bhatia AC, Desai S, Hsu TS, Kelly CT, Brazell BM, Downie J, Katz B, Woody M, Lupo M, Souyoul S, Mariwalla K, Eviatar J, Werschler WP, Schade S, Glogau RG, Jones D, Black JM, Wesley N, Kaufman-Janette J, Schlessinger J, Hall J, Perillo S, Dover J, Morton L, Solish N, Monheit G, Essig H, Yoelin S, Yoelin S. DaxibotulinumtoxinA for Injection for the Treatment of Glabellar Lines: Results from Each of Two Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Studies (SAKURA 1 and SAKURA 2). Plast Reconstr Surg. 2020 Jan;145(1):45-58. doi: 10.1097/PRS.0000000000006327. PubMed PMID: 31609882; PubMed Central PMCID: PMC6940025.
  6. Le NK, Liauw D, Siddiqui SZ, Donohue KM. Assessment of Neuromuscular Function in Patients With Prior Cosmetic Procedures: A Case Report. Eplasty. 2019;19:e20. eCollection 2019. PubMed PMID: 31885763; PubMed Central PMCID: PMC6916190.
  7. Kwon KH, Shin KS, Yeon SH, Kwon DG.  Application of botulinum toxin in maxillofacial field: Part II. Wrinkle, intraoral ulcer, and cranio-maxillofacial pain.  Maxillofac Plast Reconstr Surg. 2019 Dec;41(1):42. doi: 10.1186/s40902-019-0224-2. eCollection 2019 Dec. Review. PubMed PMID: 31649903; PubMed Central PMCID: PMC6795672.
  8. Beer KR, Shamban AT, Avelar RL, Gross JE, Jonker A.  Efficacy and Safety of PrabotulinumtoxinA for the Treatment of Glabellar Lines in Adult Subjects: Results From 2 Identical Phase III Studies.  Dermatol Surg. 2019 Nov;45(11):1381-1393. doi: 10.1097/DSS.0000000000001903. PubMed PMID: 30893162; PubMed Central PMCID: PMC6819028.
  9. Felix Bravo BS, De Bastos JT, Da Rocha CRM, Alcala B, Bianco S, Dos Santos FLL, Bravo LG. Definition of the Mandibular Angle Using Botulinum Toxin Type A: A New Technique for the Improvement of Mandibular Contour and Definition.  J Clin Aesthet Dermatol. 2019 Nov;12(11):32-34. Epub 2019 Nov 1. PubMed PMID: 32038755; PubMed Central PMCID: PMC6937167. 
  10. Park EJ, In SK, Yi HS, Kim HI, Kim HS, Kim HY.  Treatment of post-traumatic chin deformities using bilateral botulinum toxin injections.  Arch Craniofac Surg. 2019 Oct;20(5):310-313. doi: 10.7181/acfs.2019.00199. Epub 2019 Oct 20. PubMed PMID: 31658795; PubMed Central PMCID: PMC6822072.
  11. Sane S, Ali MJ, Naik MN.  Comparison of Safety and Efficacy of Botox and Neuronox in the Management of Benign Essential Blepharospasm: A Split-face Study.  Korean J Ophthalmol.2019 Oct;33(5):430-435. doi: 10.3341/kjo.2016.0123. PubMed PMID: 31612653; PubMed Central PMCID: PMC6791955.
  12. Bellows S, Jankovic J.  Immunogenicity Associated with Botulinum Toxin Treatment.  Toxins (Basel). 2019 Aug 26;11(9). doi: 10.3390/toxins11090491. Review. PubMed PMID: 31454941; PubMed Central PMCID: PMC6784164.
  13. Bulnes LC, Mariën P, Vandekerckhove M, Cleeremans A.  The effects of Botulinum toxin on the detection of gradual changes in facial emotion.  Sci Rep. 2019 Aug 13;9(1):11734. doi: 10.1038/s41598-019-48275-1. PubMed PMID: 31409880; PubMed Central PMCID: PMC6692314.
  14. Farolch-Prats L, Nome-Chamorro C. Facial Contouring by Using Dermal Fillers and Botulinum Toxin A: A Practical Approach.  Aesthetic Plast Surg. 2019 Jun;43(3):793-802. doi: 10.1007/s00266-019-01361-1. Epub 2019 Apr 5. PubMed PMID: 30953112; PubMed Central PMCID: PMC6522458.
  15. Calvani F, Santini S, Bartoletti E, Alhadeff A.  Personal Technique of Microinfiltration With Botulin Toxin: The SINB Technique (Superficial Injection Needling Botulinum).  Plast Surg (Oakv). 2019 May;27(2):156-161. doi: 10.1177/2292550318800330. Epub 2018 Oct 11. PubMed PMID: 31106174; PubMed Central PMCID: PMC6505369.
  16. Kattimani V, Tiwari RVC, Gufran K, Wasan B, Shilpa PH, Khader AA.  Botulinum Toxin Application in Facial Esthetics and Recent Treatment Indications (2013-2018).  J Int Soc Prev Community Dent. 2019 Mar-Apr;9(2):99-105. doi: 10.4103/jispcd.JISPCD_430_18. Epub 2019 Apr 12. Review. PubMed PMID: 31058058; PubMed Central PMCID: PMC6489509.
  17. Satriyasa BK.  Botulinum toxin (Botox) A for reducing the appearance of facial wrinkles: a literature review of clinical use and pharmacological aspect.  Clin Cosmet Investig Dermatol. 2019;12:223-228. doi: 10.2147/CCID.S202919. eCollection 2019. PubMed PMID: 31114283; PubMed Central PMCID: PMC6489637.
  18. Gubanova E, Haddad Tabet M, Bergerova Y, Moiseieva O, Chemeris A, Sanches E, Sharova A, Rodriguez Pose L, Raymond R, Prygova I, Carlisle I.  Assessment of Subject and Physician Satisfaction after Long-Term Treatment of Glabellar Lines with AbobotulinumtoxinA (Dysport®Azzalure®: Primary Results of the APPEAL Noninterventional Study.  Aesthetic Plast Surg. 2018 Dec;42(6):1672-1680. doi: 10.1007/s00266-018-1200-4. Epub 2018 Aug 17. PubMed PMID: 30120518; PubMed Central PMCID: PMC6280832.
  19. Lewis MB.  The interactions between botulinum-toxin-based facial treatments and embodied emotions.  Sci Rep. 2018 Oct 3;8(1):14720. doi: 10.1038/s41598-018-33119-1. PubMed PMID: 30283017; PubMed Central PMCID: PMC6170457.
  20. Chao YYY.  A Single-visit Approach Using Fillers and Incobotulinumtoxin A: Full Face Enhancement in Asian Patients.  Plast Reconstr Surg Glob Open. 2018 Oct;6(10):e1909. doi: 10.1097/GOX.0000000000001909. eCollection 2018 Oct. PubMed PMID: 30534488; PubMed Central PMCID: PMC6250484.
  21. Shome D, Khare S, Kapoor R.  An Algorithm Using Botox Injections for Facial Scar Improvement in Fitzpatrick Type IV-VI Skin.  Plast Reconstr Surg Glob Open. 2018 Aug;6(8):e1888. doi: 10.1097/GOX.0000000000001888. eCollection 2018 Aug. PubMed PMID: 30324067; PubMed Central PMCID: PMC6181490.
  22. Brennan R, Wells JSG, Van Hout M.  “Saving Face”: An Online Study of the Injecting Use of DIY Botox and Dermal Filler Kits.  Plast Surg (Oakv). 2018 Aug;26(3):154-159. doi: 10.1177/2292550318767432. Epub 2018 Apr 19. PubMed PMID: 30148126; PubMed Central PMCID: PMC6100142.
  23. Jun JY, Park JH, Youn CS, Lee JH.  Intradermal Injection of Botulinum Toxin: A Safer Treatment Modality for Forehead Wrinkles.  Ann Dermatol. 2018 Aug;30(4):458-461. doi: 10.5021/ad.2018.30.4.458. Epub 2018 Jun 28. PubMed PMID: 30065587; PubMed Central PMCID: PMC6029967.
  24.  Cao Y, Yang JP, Zhu XG, Zhu J, Chang HQ, Guo SH, Luo D, Zhou BR.  A Comparative In VivoStudy on Three Treatment Approaches to Applying Topical Botulinum Toxin A for Crow’s Feet. Biomed Res Int. 2018;2018:6235742. doi: 10.1155/2018/6235742. eCollection 2018. PubMed PMID: 30057908; PubMed Central PMCID: PMC6051279.
  25. Shetty R.  Dynamic Relaxers of the Face.    J Cutan Aesthet Surg. 2018 Apr-Jun;11(2):47-50. doi: 10.4103/JCAS.JCAS_61_18. Review. PubMed PMID: 30210205; PubMed Central PMCID: PMC6128157. 
  26. Henry N, Baker BG, Iyer S.  Frey’s syndrome following a facial burn treated with botulinum toxin.  Ann Burns Fire Disasters. 2018 Mar 31;31(1):47-48. PubMed PMID: 30174572; PubMed Central PMCID: PMC6116648.
  27. Danisi F, Guidi E.  Characterization and Treatment of Unilateral Facial Muscle Spasm in Linear Scleroderma: ACase Report.  Tremor Other Hyperkinet Mov (N Y).2018;8:531. doi: 10.7916/D88S5XJP. eCollection 2018. PubMed PMID: 29416936; PubMed Central PMCID: PMC5801335.
  28.  Seok H, Kim SG.  Correction of Malocclusion by Botulinum Neurotoxin Injection into Masticatory Muscles. Toxins (Basel). 2018 Jan 2;10(1). doi: 10.3390/toxins10010027. Review. PubMed PMID: 29301317; PubMed Central PMCID: PMC5793114.
  29.  Kim YS, Hong ES, Kim HS.  Botulinum Toxin in the Field of Dermatology: Novel Indications.  Toxins (Basel). 2017 Dec 16;9(12). doi: 10.3390/toxins9120403. Review. PubMed PMID: 29258169; PubMed Central PMCID: PMC5744123.
  30.  Mess SA.  Lower Face Rejuvenation with Injections: Botox, Juvederm, and Kybella for Marionette Lines and Jowls.  Plast Reconstr Surg Glob Open. 2017 Nov;5(11):e1551. doi: 10.1097/GOX.0000000000001551. eCollection 2017 Nov. PubMed PMID: 29263958; PubMed Central PMCID: PMC5732664.
  31. Anido J, Arenas D, Arruabarrena C, Domínguez-Gil A, Fajardo C, Mira M, Murillo J, Ribé N, Rivera H, Ruiz Del Cueto S, Silvestre H, Tirado M.  Tailored botulinum toxin type A injections in aesthetic medicine: consensus panel recommendations for treating the forehead based on individual facial anatomy and muscle tone.  Clin Cosmet Investig Dermatol. 2017;10:413-421. doi: 10.2147/CCID.S138274. eCollection 2017. PubMed PMID: 29089780; PubMed Central PMCID: PMC5655032.
  32. Lim JTE, Loh DK, Soh K, Sunga O.  Efficacy and patient satisfaction with incobotulinumtoxinA for the treatment of glabellar frown lines.  Singapore Med J. 2017 Oct;58(10):606-609. doi: 10.11622/smedj.2016112. Epub 2016 Jun 29. PubMed PMID: 27357317; PubMed Central PMCID: PMC5651507.
  33. Harii K, Kawashima M, Furuyama N, Lei X, Hopfinger R, Lee E.  OnabotulinumtoxinA (Botox) in the Treatment of Crow’s Feet Lines in Japanese Subjects.  Aesthetic Plast Surg. 2017 Oct;41(5):1186-1197. doi: 10.1007/s00266-017-0844-9. Epub 2017 Jul 21. PubMed PMID: 28733805; PubMed Central PMCID: PMC5605642.
  34. Chao YYY, Chhabra C, Corduff N, Fabi SG, Kerscher M, Lam SCK, Pavicic T, Rzany B, Peng PHL, Suwanchinda A, Tseng FW, Seo KK. PAN-ASIAN CONSENSUS-Key Recommendations for Adapting the World Congress of Dermatology Consensus on Combination Treatment With Injectable Fillers, Toxins, and Ultrasound Devices in Asian Patient
  35.  J Clin Aesthet Dermatol. 2017 Aug;10(8):16-27. Epub 2017 Aug 1. PubMed PMID: 28979659; PubMed Central PMCID: PMC5605210. Schlessinger J, Gilbert E, Cohen JL, Kaufman J.  New Uses of AbobotulinumtoxinA in Aesthetics. Aesthet Surg J. 2017 May 1;37(suppl_1):S45-S58. doi: 10.1093/asj/sjx005. Review. PubMed PMID: 28388720; PubMed Central PMCID: PMC5434494.
  36. Nestor M, Ablon G, Pickett A.  Key Parameters for the Use of AbobotulinumtoxinA in Aesthetics: Onset and Duration. Aesthet Surg J. 2017 May 1;37(suppl_1):S20-S31. doi: 10.1093/asj/sjw282. Review. PubMed PMID: 28388717; PubMed Central PMCID: PMC5434495.
  37. Monheit GD, Pickett A.  AbobotulinumtoxinA : A 25-Year History.  Aesthet Surg J. 2017 May 1;37(suppl_1):S4-S11. doi: 10.1093/asj/sjw284. Review. PubMed PMID: 28388718; PubMed Central PMCID: PMC5434488.
  38. Kane MA, Monheit G.  The Practical Use of AbobotulinumtoxinA in Aesthetics.  Aesthet Surg J. 2017 May 1;37(suppl_1):S12-S19. doi: 10.1093/asj/sjw285. Review. PubMed PMID: 28388719; PubMed Central PMCID: PMC5434487.
  39.  Cohen JL, Scuderi N.  Safety and Patient Satisfaction of AbobotulinumtoxinA for Aesthetic Use: A Systematic Review.  Aesthet Surg J. 2017 May 1;37(suppl_1):S32-S44. doi: 10.1093/asj/sjx010. Review. PubMed PMID: 28388721; PubMed Central PMCID: PMC5434490.
  40. Sapra P, Demay S, Sapra S, Khanna J, Mraud K, Bonadonna J.  A Single-blind, Split-face, Randomized, Pilot Study Comparing the Effects of Intradermal and Intramuscular Injection of Two Commercially Available Botulinum Toxin A Formulas to Reduce Signs of Facial Aging.  J Clin Aesthet Dermatol. 2017 Feb;10(2):34-44. Epub 2017 Feb 1. PubMed PMID: 28367260; PubMed Central PMCID: PMC5367871.
  41. Susmita A, Kolli NN, Meka S, Chakravarthi SP, Kattimani VS, Lingamaneni KP, Shaik LS.  An Evaluation of Use of Botulinum Toxin Type A in the Management of Dynamic Forehead Wrinkles – A Clinical Study.  J Clin Diagn Res. 2016 Oct;10(10):ZC127-ZC131. doi: 10.7860/JCDR/2016/21904.8695. Epub 2016 Oct 1. PubMed PMID: 27891474; PubMed Central PMCID: PMC5121792.
  42. Sundaram H, Liew S, Signorini M, Vieira Braz A, Fagien S, Swift A, De Boulle KL, Raspaldo H, Trindade de Almeida AR, Monheit G.  Global Aesthetics Consensus: Hyaluronic Acid Fillers and Botulinum Toxin Type A-Recommendations for Combined Treatment and Optimizing Outcomes in Diverse Patient Populations. Plast Reconstr Surg. 2016 May;137(5):1410-23. doi: 10.1097/PRS.0000000000002119. PubMed PMID: 27119917; PubMed Central PMCID: PMC5242215.
  43. Elhefnawy AM.  Assessment of intralesional injection of botulinum toxin type A injection for hypertrophic scars.;year=2016;volume=82;issue=3;spage=279;epage=283;aulast=Elhefnawy  Indian J Dermatol Venereol Leprol. 2016 May-Jun;82(3):279-83. doi: 10.4103/0378-6323.173586. PubMed PMID: 27088929.
  44. Sundaram H, Signorini M, Liew S, Trindade de Almeida AR, Wu Y, Vieira Braz A, Fagien S, Goodman GJ, Monheit G, Raspaldo H.  Global Aesthetics Consensus: Botulinum Toxin Type A–Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications.  Plast Reconstr Surg. 2016 Mar;137(3):518e-529e. doi: 10.1097/01.prs.0000475758.63709.23. Review. PubMed PMID: 26910696; PubMed Central PMCID: PMC5242214.
  45. Chuang J, Barnes C, Wong BJF. Overview of Facial Plastic Surgery and Current Developments. Surg J (N Y). 2016 Mar;2(1):e17-e28. doi: 10.1055/s-0036-1572360. eCollection 2016 Mar. Review. PubMed PMID: 28824978; PubMed Central PMCID: PMC5553462.
  46. Kuwahara H, Ogawa R.  Using a Vibration Device to Ease Pain During Facial Needling and Injection.  Eplasty. 2016;16:e9. eCollection 2016. PubMed PMID: 26933468; PubMed Central PMCID: PMC4750366.
  47. Namazi N, Robati RM, Dadkhahfar S, Shafiee A, Bidari-Zerehpoush F.  Vasculitis with panniculitis following botulinum toxin A injection for cosmetic use.  Dermatol Pract Concept. 2016 Jan;6(1):19-21. doi: 10.5826/dpc.0601a06. eCollection 2016 Jan. PubMed PMID: 26937303; PubMed Central PMCID: PMC4758441.
  48. Punga AR, Eriksson A, Alimohammadi M.  Regional diffusion of botulinum toxin in facial muscles: a randomised double-blind study and a consideration for clinical studies with split-face design.  Acta Derm Venereol. 2015 Nov;95(8):948-51. doi: 10.2340/00015555-2093. PubMed PMID: 25766591.
  49. Resistance to Botulinum Toxin in Aesthetics
  50. AbobotulinumtoxinA (Dysport ®), OnabotulinumtoxinA (Botox ®), and IncobotulinumtoxinA (Xeomin ®) Neurotoxin Content and Potential Implications for Duration of Response in Patients
  51.  Botulinum Toxin in Aesthetic Medicine: Myths and Realities
  52.  This Mysterious Botox
  53.  Botulinum Neurotoxin Therapy for Lingual Dystonia Using an Individualized Injection Method Based on Clinical Features
Dermal Filler Studies

Clinical studies involving dermal fillers you can study to further expand your knowledge.